About Help FAQ

Symbol
Name
ID

Pklr
pyruvate kinase liver and red blood cell
MGI:97604

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Polyclonal elevation of IgM	Increased circulating antibody level	Leukocytosis	Leukopenia	Impaired neutrophil bactericidal activity	Splenic infarction	Splenic rupture	Splenomegaly	Hepatitis	Osteomyelitis
Disease(s) Associated with PKLR	Polyclonal elevation of IgM	Increased circulating antibody level	Leukocytosis	Leukopenia	Impaired neutrophil bactericidal activity	Splenic infarction	Splenic rupture	Splenomegaly	Hepatitis	Osteomyelitis
congenital nonspherocytic hemolytic anemia
Gaucher's disease
pyruvate kinase deficiency of red cells

Mouse Phenotypes		enlarged spleen	increased susceptibility to bacterial infection induced morbidity/mortality	decreased susceptibility to parasitic infection induced morbidity/mortality	decreased susceptibility to parasitic infection
Availability	Mouse Genotype	enlarged spleen			decreased susceptibility to parasitic infection
	Pklr^char4/Pklr^char4
	Pklr^slc/Pklr^slc

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23